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Differential signaling mechanism for HIV-1 Nef-mediated production of IL-6 and IL-8 in human astrocytes
Variety of HIV-1 viral proteins including HIV-1 Nef are known to activate astrocytes and microglia in the brain and cause the release of pro-inflammatory cytokines, which is thought to be one of the mechanisms leading to HIV-1- mediated neurotoxicity. IL-6 and IL-8 have been found in the CSF of pati...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467202/ https://ncbi.nlm.nih.gov/pubmed/26075907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09867 |
| Oznake: |
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