Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes

Methamphetamine (MA) is one of the commonly used illicit drugs and the central nervous system toxicity of MA is well documented. The mechanisms contributing to this toxicity have not been fully elucidated. In this study, we investigated the effect of MA on the expression levels of the proinflammator...

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Detalhes bibliográficos
Main Authors: Shah, Ankit, Silverstein, Peter S, Singh, Dhirendra P, Kumar, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338363/
https://ncbi.nlm.nih.gov/pubmed/22420994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-52
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