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Synergistic Cooperation between Methamphetamine and HIV-1 gsp120 through the P13K/Akt Pathway Induces IL-6 but not IL-8 Expression in Astrocytes

HIV-1 envelope protein gp120 has been extensively studied for neurotoxic effects that have been attributed to the increased expression of various proinflammatory cytokines in the CNS. Recently we have shown that methamphetamine (MA) also increases expression of proinflammatory cytokines in astrocyte...

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Detalhes bibliográficos
Main Authors: Shah, Ankit, Silverstein, Peter S., Kumar, Santosh, Singh, Dhirendra P., Kumar, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522628/
https://ncbi.nlm.nih.gov/pubmed/23251686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052060
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