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Molecular mechanisms involved in HIV-1 Tat-mediated induction of IL-6 and IL-8 in astrocytes

BACKGROUND: HIV-associated neurocognitive disorders (HAND) exist in approximately 50% of infected individuals even after the introduction of highly active antiretroviral therapy. HIV-1 Tat has been implicated in HIV-associated neurotoxicity mediated through production of pro-inflammatory cytokines l...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Nookala, Anantha Ram, Kumar, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302610/
https://ncbi.nlm.nih.gov/pubmed/25539898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0214-3
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