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Multiple Protein Kinases via Activation of Transcription Factors NF-κB, AP-1 and C/EBP-δ Regulate the IL-6/IL-8 Production by HIV-1 Vpr in Astrocytes

Neurocognitive impairments affect a substantial population of HIV-1 infected individuals despite the success of anti-retroviral therapy in controlling viral replication. Astrocytes are emerging as a crucial cell type that might be playing a very important role in the persistence of neuroinflammation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gangwani, Mohitkumar R., Kumar, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535882/
https://ncbi.nlm.nih.gov/pubmed/26270987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135633
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