Global analysis of H3K4me3 and H3K27me3 profiles in glioblastoma stem cells and identification of SLC17A7 as a bivalent tumor suppressor gene

Epigenetic changes, including H3K4me3 and H3K27me3 histone modification, play an important role in carcinogenesis. However, no genome-wide histone modification map has been generated for gliomas. Here, we report a genome-wide map of H3K4me3 and H3K27me3 histone modifications for 8 glioma stem cell (...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lin, Biaoyang, Lee, Hwahyung, Yoon, Jae-Geun, Madan, Anup, Wayner, Elizabeth, Tonning, Sanja, Hothi, Parvinder, Schroeder, Brett, Ulasov, Ilya, Foltz, Gregory, Hood, Leroy, Cobbs, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467155/
https://ncbi.nlm.nih.gov/pubmed/25749033
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