Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in Mice

Current monitoring of acute lymphoblastic leukemia (ALL) in living mice is based on FACS analysis of blood hCD45+ cells. In this work, we evaluated the use of human IGFBP2, B2M or Hsp90 as soluble markers of leukemia. ELISA for B2M and IGFBP2 resulted in high background levels in healthy animals, pr...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Milani, Mateus, Laranjeira, Angelo Brunelli Albertoni, de Vasconcellos, Jaíra Ferreira, Brandalise, Silvia Regina, Nowill, Alexandre Eduardo, Yunes, José Andrés
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466233/
https://ncbi.nlm.nih.gov/pubmed/26068922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129298
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