Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in Mice

Current monitoring of acute lymphoblastic leukemia (ALL) in living mice is based on FACS analysis of blood hCD45+ cells. In this work, we evaluated the use of human IGFBP2, B2M or Hsp90 as soluble markers of leukemia. ELISA for B2M and IGFBP2 resulted in high background levels in healthy animals, pr...

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Publicado en:PLoS One
Autores principales: Milani, Mateus, Laranjeira, Angelo Brunelli Albertoni, de Vasconcellos, Jaíra Ferreira, Brandalise, Silvia Regina, Nowill, Alexandre Eduardo, Yunes, José Andrés
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466233/
https://ncbi.nlm.nih.gov/pubmed/26068922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129298
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