Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway

Atherosclerotic lesions are accelerated in patients with diabetes. M1 (classically activated in contrast to M2 alternatively activated) macrophages play key roles in the progression of atherosclerosis. Since advanced glycation end products (AGEs) are major pathogenic factors and active inflammation...

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Dades bibliogràfiques
Publicat a:Biomed Res Int
Autors principals: Jin, Xian, Yao, Tongqing, Zhou, Zhong'e, Zhu, Jian, Zhang, Song, Hu, Wei, Shen, Chengxing
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465680/
https://ncbi.nlm.nih.gov/pubmed/26114112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/732450
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