Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression

Advanced glycation end products (AGEs) are major inflammatory mediators in diabetes, affecting atherosclerosis progression via macrophages. Metformin slows diabetic atherosclerosis progression through mechanisms that remain to be fully elucidated. The present study of murine bone marrow derived macr...

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Vydáno v:J Diabetes Res
Hlavní autoři: Zhou, Zhong'e, Tang, Yong, Jin, Xian, Chen, Chengjun, Lu, Yi, Liu, Liang, Shen, Chengxing
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059570/
https://ncbi.nlm.nih.gov/pubmed/27761470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4847812
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