Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression

Advanced glycation end products (AGEs) are major inflammatory mediators in diabetes, affecting atherosclerosis progression via macrophages. Metformin slows diabetic atherosclerosis progression through mechanisms that remain to be fully elucidated. The present study of murine bone marrow derived macr...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Zhou, Zhong'e, Tang, Yong, Jin, Xian, Chen, Chengjun, Lu, Yi, Liu, Liang, Shen, Chengxing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059570/
https://ncbi.nlm.nih.gov/pubmed/27761470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4847812
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