Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

Accumulating evidence is indicating metformin to possess the potential ability in preventing tumor development and suppressing cancer growth. However, the exact mechanism of its antitumorigenic effects is still not clear. We found that metformin suppressed the ability of cancer to skew macrophage to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chiang, Chi-Fu, Chao, Ting-Ting, Su, Yu-Fu, Hsu, Chia-Chen, Chien, Chu-Yen, Chiu, Kuo-Chou, Shiah, Shine-Gwo, Lee, Chien-Hsing, Liu, Shyun-Yeu, Shieh, Yi-Shing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400538/
https://ncbi.nlm.nih.gov/pubmed/28157701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14982
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