Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

Accumulating evidence is indicating metformin to possess the potential ability in preventing tumor development and suppressing cancer growth. However, the exact mechanism of its antitumorigenic effects is still not clear. We found that metformin suppressed the ability of cancer to skew macrophage to...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Chiang, Chi-Fu, Chao, Ting-Ting, Su, Yu-Fu, Hsu, Chia-Chen, Chien, Chu-Yen, Chiu, Kuo-Chou, Shiah, Shine-Gwo, Lee, Chien-Hsing, Liu, Shyun-Yeu, Shieh, Yi-Shing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400538/
https://ncbi.nlm.nih.gov/pubmed/28157701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14982
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