Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway

Atherosclerotic lesions are accelerated in patients with diabetes. M1 (classically activated in contrast to M2 alternatively activated) macrophages play key roles in the progression of atherosclerosis. Since advanced glycation end products (AGEs) are major pathogenic factors and active inflammation...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Jin, Xian, Yao, Tongqing, Zhou, Zhong'e, Zhu, Jian, Zhang, Song, Hu, Wei, Shen, Chengxing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465680/
https://ncbi.nlm.nih.gov/pubmed/26114112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/732450
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