A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion ()

Efforts to identify host determinants for malaria have been hindered by the absence of a nucleus in erythrocytes, precluding genetic manipulation in the cell where the parasite replicates. We used cultured red blood cells derived from hematopoietic stem cells to carry out a forward genetic screen fo...

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書誌詳細
出版年:Science
主要な著者: Egan, Elizabeth S., Jiang, Rays H.Y., Moechtar, Mischka A., Barteneva, Natasha S., Weekes, Michael P., Nobre, Luis V., Gygi, Steven P., Paulo, Joao A., Frantzreb, Charles, Tani, Yoshihiko, Takahashi, Junko, Watanabe, Seishi, Goldberg, Jonathan, Paul, Aditya S., Brugnara, Carlo, Root, David E., Wiegand, Roger C., Doench, John G., Duraisingh, Manoj T.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465434/
https://ncbi.nlm.nih.gov/pubmed/25954012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa3526
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