Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum

The ATP-binding cassette transporter ABCB6 was recently discovered to encode the Langereis (Lan) blood group antigen. Lan null individuals are asymptomatic, and the function of ABCB6 in mature erythrocytes is not understood. Here, we assessed ABCB6 as a host factor for Plasmodium falciparum malaria...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Egan, Elizabeth S., Weekes, Michael P., Kanjee, Usheer, Manzo, Jale, Srinivasan, Ashwin, Lomas-Francis, Christine, Westhoff, Connie, Takahashi, Junko, Tanaka, Mitsunobu, Watanabe, Seishi, Brugnara, Carlo, Gygi, Steven P., Tani, Yoshihiko, Duraisingh, Manoj T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123700/
https://ncbi.nlm.nih.gov/pubmed/30271928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0046-2
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