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New tricks for p53 regulation – restraint by protein coding RNAs

P53 is most well-known for its tumor suppressive function in differentiated cells. Its activities in embryonic stem cells (ESCs) are, however, less well understood. For many years it was thought that p53 is not active at all in ESCs and unable to elicit a DNA damage response in this cell type. In th...

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Detalles Bibliográficos
Publicado en:Cell Biosci
Autor Principal: Blattner, Christine
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465304/
https://ncbi.nlm.nih.gov/pubmed/26075053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0022-1
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