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New tricks of an old molecule: lifespan regulation by p53
As guardian of the genome the tumor suppressor p53 controls a crucial point in protection from cellular damage and response to stressors. Activation of p53 can have beneficial (DNA repair) or detrimental (apoptosis) consequences for individual cells. In either case activation of p53 is thought to sa...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Publishing Ltd
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592233/ https://ncbi.nlm.nih.gov/pubmed/16968311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2006.00228.x |
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