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New tricks for p53 regulation – restraint by protein coding RNAs

P53 is most well-known for its tumor suppressive function in differentiated cells. Its activities in embryonic stem cells (ESCs) are, however, less well understood. For many years it was thought that p53 is not active at all in ESCs and unable to elicit a DNA damage response in this cell type. In th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Biosci
Prif Awdur: Blattner, Christine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465304/
https://ncbi.nlm.nih.gov/pubmed/26075053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0022-1
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