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Regulation of p53 by E3s

SIMPLE SUMMARY: The p53 protein is a transcription factor that initiates cell cycle arrest and apoptosis and by this counteracts tumorigenesis. Because of its anti-proliferative activity, p53 levels are usually low as the protein is rapidly degraded, unless its anti-tumoral activity is required. E3s...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Pan, Mengwu, Blattner, Christine
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916862/
https://ncbi.nlm.nih.gov/pubmed/33670160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040745
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