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New tricks of an old molecule: lifespan regulation by p53

As guardian of the genome the tumor suppressor p53 controls a crucial point in protection from cellular damage and response to stressors. Activation of p53 can have beneficial (DNA repair) or detrimental (apoptosis) consequences for individual cells. In either case activation of p53 is thought to sa...

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Detalles Bibliográficos
Main Authors: Bauer, Johannes H, Helfand, Stephen L
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592233/
https://ncbi.nlm.nih.gov/pubmed/16968311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2006.00228.x
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