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Dominant Alcohol-Protein Interaction via Hydration-Enabled Enthalpy-Driven Binding Mechanism

Water plays an important role in weak associations of small drug molecules with proteins. Intense focus has been on binding-induced structural changes in the water network surrounding protein binding sites, especially their contributions to binding thermodynamics. However, water is also tightly coup...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Phys Chem B
Päätekijät: Chong, Yuan, Kleinhammes, Alfred, Tang, Pei, Xu, Yan, Wu, Yue
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465287/
https://ncbi.nlm.nih.gov/pubmed/25856773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b00378
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