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Critical Role of Water in the Binding of Volatile Anesthetics to Proteins
Numerous small molecules exhibit drug-like properties by low-affinity binding to proteins. Such binding is known to be influenced by water, the detailed picture of which, however, remains unclear. One particular example is the controversial role of water in the binding of general anesthetics to prot...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901425/ https://ncbi.nlm.nih.gov/pubmed/24050264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp407115j |
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