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Balance between hydration enthalpy and entropy is important for ice binding surfaces in Antifreeze Proteins

Antifreeze Proteins (AFPs) inhibit the growth of an ice crystal by binding to it. The detailed binding mechanism is, however, still not fully understood. We investigated three AFPs using Molecular Dynamics simulations in combination with Grid Inhomogeneous Solvation Theory, exploring their hydration...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Schauperl, Michael, Podewitz, Maren, Ortner, Teresa S., Waibl, Franz, Thoeny, Alexander, Loerting, Thomas, Liedl, Klaus R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605524/
https://ncbi.nlm.nih.gov/pubmed/28928396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11982-8
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