Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut

ω3 polyunsaturated fatty acids (PUFAs) have anti-allergic and anti-inflammatory properties, but the immune-metabolic progression from dietary oil remains to be investigated. Here we identified 17,18-epoxyeicostetraenoic acid (17,18-EpETE) as an anti-allergic metabolite generated in the gut from diet...

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Publicado no:Sci Rep
Main Authors: Kunisawa, Jun, Arita, Makoto, Hayasaka, Takahiro, Harada, Takashi, Iwamoto, Ryo, Nagasawa, Risa, Shikata, Shiori, Nagatake, Takahiro, Suzuki, Hidehiko, Hashimoto, Eri, Kurashima, Yosuke, Suzuki, Yuji, Arai, Hiroyuki, Setou, Mitsutoshi, Kiyono, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464255/
https://ncbi.nlm.nih.gov/pubmed/26065911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09750
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