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The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis

Intestinal epithelial cells (IECs) have critical roles in maintaining homeostasis of intestinal epithelium. Endoplasmic reticulum (ER) stress is implicated in intestinal epithelium homeostasis and inflammatory bowel disease; however, it remains elusive whether IRE1α, a major sensor of ER stress, is...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Zhang, Hai-Sheng, Chen, Ying, Fan, Li, Xi, Qiu-Lei, Wu, Guo-Hao, Li, Xiu-Xiu, Yuan, Tang-Long, He, Sheng-Qi, Yu, Yue, Shao, Meng-Le, Liu, Yang, Bai, Chen-Guang, Ling, Zhi-Qiang, Li, Min, Liu, Yong, Fang, Jing
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463471/
https://ncbi.nlm.nih.gov/pubmed/25925952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633560
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