The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis

Intestinal epithelial cells (IECs) have critical roles in maintaining homeostasis of intestinal epithelium. Endoplasmic reticulum (ER) stress is implicated in intestinal epithelium homeostasis and inflammatory bowel disease; however, it remains elusive whether IRE1α, a major sensor of ER stress, is...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Hai-Sheng, Chen, Ying, Fan, Li, Xi, Qiu-Lei, Wu, Guo-Hao, Li, Xiu-Xiu, Yuan, Tang-Long, He, Sheng-Qi, Yu, Yue, Shao, Meng-Le, Liu, Yang, Bai, Chen-Guang, Ling, Zhi-Qiang, Li, Min, Liu, Yong, Fang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463471/
https://ncbi.nlm.nih.gov/pubmed/25925952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633560
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