The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis

Intestinal epithelial cells (IECs) have critical roles in maintaining homeostasis of intestinal epithelium. Endoplasmic reticulum (ER) stress is implicated in intestinal epithelium homeostasis and inflammatory bowel disease; however, it remains elusive whether IRE1α, a major sensor of ER stress, is...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Zhang, Hai-Sheng, Chen, Ying, Fan, Li, Xi, Qiu-Lei, Wu, Guo-Hao, Li, Xiu-Xiu, Yuan, Tang-Long, He, Sheng-Qi, Yu, Yue, Shao, Meng-Le, Liu, Yang, Bai, Chen-Guang, Ling, Zhi-Qiang, Li, Min, Liu, Yong, Fang, Jing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Cell Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463471/
https://ncbi.nlm.nih.gov/pubmed/25925952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633560
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