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Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
Accumulation of misfolded proteins in the endoplasmic reticulum (ER) triggers the unfolded protein response (UPR), an intracellular signaling pathway that adjusts the protein folding capacity of the ER according to need. If homeostasis in the ER protein folding environment cannot be reestablished, c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941319/ https://ncbi.nlm.nih.gov/pubmed/20798350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010580107 |
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