Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses

Elongin A performs dual functions in cells as a component of RNA polymerase II (Pol II) transcription elongation factor Elongin and as the substrate recognition subunit of a Cullin-RING E3 ubiquitin ligase that has been shown to target Pol II stalled at sites of DNA damage. Here we investigate the m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Weems, Juston C., Slaughter, Brian D., Unruh, Jay R., Hall, Shawn M., McLaird, Merry B., Gilmore, Joshua M., Washburn, Michael P., Florens, Laurence, Yasukawa, Takashi, Aso, Teijiro, Conaway, Joan W., Conaway, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463447/
https://ncbi.nlm.nih.gov/pubmed/25878247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632794
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados