Integrated compensatory network is activated in the absence of NCC phosphorylation

Thiazide diuretics are used to treat hypertension; however, compensatory processes in the kidney can limit antihypertensive responses to this class of drugs. Here, we evaluated compensatory pathways in SPAK kinase–deficient mice, which are unable to activate the thiazide-sensitive sodium chloride co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Grimm, P. Richard, Lazo-Fernandez, Yoskaly, Delpire, Eric, Wall, Susan M., Dorsey, Susan G., Weinman, Edward J., Coleman, Richard, Wade, James B., Welling, Paul A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463200/
https://ncbi.nlm.nih.gov/pubmed/25893600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78558
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