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Increasing plasma [K(+)] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis

Dietary potassium loading results in rapid kaliuresis, natriuresis, and diuresis associated with reduced phosphorylation (p) of the distal tubule Na(+)-Cl(−) cotransporter (NCC). Decreased NCC-p inhibits NCC-mediated Na(+) reabsorption and shifts Na(+) downstream for reabsorption by epithelial Na(+)...

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Detalhes bibliográficos
Main Authors: Rengarajan, Srinivas, Lee, Donna H., Oh, Young Taek, Delpire, Eric, Youn, Jang H., McDonough, Alicia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010681/
https://ncbi.nlm.nih.gov/pubmed/24598799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00015.2014
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