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Structural Insight into an Alzheimer’s Brain-Derived Spherical Assembly of Amyloid β by Solid-State NMR

[Image: see text] Accumulating evidence suggests that various neurodegenerative diseases, including Alzheimer’s disease (AD), are linked to cytotoxic diffusible aggregates of amyloid proteins, which are metastable intermediate species in protein misfolding. This study presents the first site-specifi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Am Chem Soc
Main Authors: Parthasarathy, Sudhakar, Inoue, Masafumi, Xiao, Yiling, Matsumura, Yoshitaka, Nabeshima, Yo-ichi, Hoshi, Minako, Ishii, Yoshitaka
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2015
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462565/
https://ncbi.nlm.nih.gov/pubmed/25938164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03373
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