Use of Robotized DNA Isolation and Real-Time PCR To Quantify and Identify Close Correlation between Levels of Neisseria meningitidis DNA and Lipopolysaccharides in Plasma and Cerebrospinal Fluid from Patients with Systemic Meningococcal Disease

The present study, using robotized DNA isolation and quantitative PCR based on the Neisseria meningitidis-specific capsular transport A gene, demonstrates the ease, rapidity, specificity, and sensitivity of quantifying neisserial DNA in plasma (n = 65) and cerebrospinal fluid (CSF) (n = 12) from pat...

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Bibliographische Detailangaben
Hauptverfasser: Øvstebø, Reidun, Brandtzaeg, Petter, Brusletto, Berit, Haug, Kari Bente Foss, Lande, Knut, Høiby, Ernst Arne, Kierulf, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Bacteriology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC446236/
https://ncbi.nlm.nih.gov/pubmed/15243048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.7.2980-2987.2004
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