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Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype

BACKGROUND: MMTV-Wnt1 transgenic mice develop mammary hyperplasia early in development, followed by the appearance of solitary mammary tumors with a high proportion of cells expressing early lineage markers and many myoepithelial cells. The occurrence of tumors is accelerated in experiments that act...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Podsypanina, Katrina, Li, Yi, Varmus, Harold E
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC446228/
https://ncbi.nlm.nih.gov/pubmed/15198801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-2-24
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