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Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype

BACKGROUND: MMTV-Wnt1 transgenic mice develop mammary hyperplasia early in development, followed by the appearance of solitary mammary tumors with a high proportion of cells expressing early lineage markers and many myoepithelial cells. The occurrence of tumors is accelerated in experiments that act...

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Detalles Bibliográficos
Publicado en:BMC Med
Autores principales: Podsypanina, Katrina, Li, Yi, Varmus, Harold E
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC446228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15198801/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1741-7015-2-24
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