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Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype

BACKGROUND: MMTV-Wnt1 transgenic mice develop mammary hyperplasia early in development, followed by the appearance of solitary mammary tumors with a high proportion of cells expressing early lineage markers and many myoepithelial cells. The occurrence of tumors is accelerated in experiments that act...

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Autors principals: Podsypanina, Katrina, Li, Yi, Varmus, Harold E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC446228/
https://ncbi.nlm.nih.gov/pubmed/15198801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-2-24
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