Knockdown or inhibition of Aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras - E-cadherin pathway

Aldo-keto reductase 1B10 (AKR1B10) has relatively specific lipid substrates including carbonyls, retinal and farnesal/geranylgeranial. Metabolizing these lipid substrates appears crucial to carcinogenesis, particularly for farnesal/geranylgeranial that involves in protein prenylation. Mutant Kras is...

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Detaylı Bibliyografya
Yayımlandı:Cancer Lett
Asıl Yazarlar: Zhang, Wanying, Li, Haonan, Yang, Yihe, Liao, Jie, Yang, Guang-Yu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462172/
https://ncbi.nlm.nih.gov/pubmed/25304374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.031
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