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Knockdown or inhibition of Aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras - E-cadherin pathway
Aldo-keto reductase 1B10 (AKR1B10) has relatively specific lipid substrates including carbonyls, retinal and farnesal/geranylgeranial. Metabolizing these lipid substrates appears crucial to carcinogenesis, particularly for farnesal/geranylgeranial that involves in protein prenylation. Mutant Kras is...
Gardado en:
| Publicado en: | Cancer Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4462172/ https://ncbi.nlm.nih.gov/pubmed/25304374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.031 |
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