Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors

Despite gains in survival, outcomes for patients with metastatic or recurrent rhabdomyosarcoma (RMS) remain dismal. In a collaboration between the National Cancer Institute, Children's Oncology Group, and Broad Institute, we performed whole-genome, whole-exome and transcriptome sequencing to ch...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Shern, Jack F., Chen, Li, Chmielecki, Juliann, Wei, Jun S., Patidar, Rajesh, Rosenberg, Mara, Ambrogio, Lauren, Auclair, Daniel, Wang, Jianjun, Song, Young K., Tolman, Catherine, Hurd, Laura, Liao, Hongling, Zhang, Shile, Bogen, Dominik, Brohl, Andrew S., Sindiri, Sivasish, Catchpoole, Daniel, Badgett, Thomas, Getz, Gad, Mora, Jaume, Anderson, James R., Skapek, Stephen X., Barr, Frederic G., Meyerson, Matthew, Hawkins, Douglas S., Khan, Javed
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462130/
https://ncbi.nlm.nih.gov/pubmed/24436047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0639
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