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Differential DNA methylation profile of key genes in malignant prostate epithelial cells transformed by inorganic arsenic or cadmium

Previous work shows altered methylation patterns in inorganic arsenic (iAs)-or cadmium (Cd)-transformed epithelial cells. Here, the methylation status near the transcriptional start site was assessed in the normal human prostate epithelial cell line (RWPE-1) that was malignantly transformed by 10 μM...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Pelch, Katherine E., Tokar, Erik J., Merrick, B. Alex, Waalkes, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461502/
https://ncbi.nlm.nih.gov/pubmed/25922126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.04.011
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