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Structure of the catalytic domain of Mre11 from Chaetomium thermophilum

Together with the Rad50 ATPase, the Mre11 nuclease forms an evolutionarily conserved protein complex that plays a central role in the repair of DNA double-strand breaks (DSBs). Mre11–Rad50 detects and processes DNA ends, and has functions in the tethering as well as the signalling of DSBs. The Mre11...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Seifert, Florian Ulrich, Lammens, Katja, Hopfner, Karl-Peter
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461342/
https://ncbi.nlm.nih.gov/pubmed/26057807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15007566
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