Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic

Recent studies have conferred that the RAD51C and RAD51D genes, which code for the essential proteins involved in homologous recombination, are ovarian cancer (OC) susceptibility genes that may explain genetic risks in high-risk patients. We performed a mutation analysis in 171 high-risk BRCA1 and B...

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Veröffentlicht in:PLoS One
Hauptverfasser: Janatova, Marketa, Soukupova, Jana, Stribrna, Jana, Kleiblova, Petra, Vocka, Michal, Boudova, Petra, Kleibl, Zdenek, Pohlreich, Petr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461297/
https://ncbi.nlm.nih.gov/pubmed/26057125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127711
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