High proportion of recurrent germline mutations in the BRCA1 gene in breast and ovarian cancer patients from the Prague area

BACKGROUND: Germline mutations in the BRCA1 and BRCA2 genes have been shown to account for the majority of hereditary breast and ovarian cancers. The purpose of our study was to estimate the incidence and spectrum of pathogenic mutations in BRCA1/2 genes in high-risk Czech families. METHODS: A total...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pohlreich, Petr, Zikan, Michal, Stribrna, Jana, Kleibl, Zdenek, Janatova, Marketa, Kotlas, Jaroslav, Zidovska, Jana, Novotny, Jan, Petruzelka, Lubos, Szabo, Csilla, Matous, Bohuslav
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2005
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242140/
https://ncbi.nlm.nih.gov/pubmed/16168118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1282
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak