Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic

Recent studies have conferred that the RAD51C and RAD51D genes, which code for the essential proteins involved in homologous recombination, are ovarian cancer (OC) susceptibility genes that may explain genetic risks in high-risk patients. We performed a mutation analysis in 171 high-risk BRCA1 and B...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Janatova, Marketa, Soukupova, Jana, Stribrna, Jana, Kleiblova, Petra, Vocka, Michal, Boudova, Petra, Kleibl, Zdenek, Pohlreich, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461297/
https://ncbi.nlm.nih.gov/pubmed/26057125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127711
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