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The Virion Host Shutoff Protein of Herpes Simplex Virus Type 1 Has RNA Degradation Activity in Primary Neurons
The virion host shutoff protein (Vhs) of herpes simplex virus type 1 induces destabilization of mRNA following infection. Our study of primary neurons from CD-1 mice demonstrates that vhs is functional in neurons but that more Vhs is required to mediate RNA degradation in neurons than in other susce...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC446108/ https://ncbi.nlm.nih.gov/pubmed/15254212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.15.8400-8403.2004 |
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