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A Functional Switch From Lung Cancer Resistance to Susceptibility at the Pas1 Locus in Kras2(LA2) Mice
Pulmonary adenoma susceptibility 1 (Pas1) is the major mouse lung cancer susceptibility locus on chromosome 6 (ref. 1), spanning a region containing six genes(2), one of which is Kras2. Kras2 is a common target of somatic mutation in chemically induced mouse lung tumors(3,4), and is a candidate Pas1...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461000/ https://ncbi.nlm.nih.gov/pubmed/16823377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1836 |
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