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Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer

Alterations in DNA copy number contribute to the development and progression of cancers and are common in epithelial tumors. We have used array Comparative Genomic Hybridization (aCGH) to visualize DNA copy number alterations across the genomes of lung tumors in the Kras(LA2) model of lung cancer. C...

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Detalhes bibliográficos
Main Authors: To, Minh D., Quigley, David A., Mao, Jian-Hua, Rosario, Reyno Del, Hsu, Jeff, Hodgson, Graeme, Jacks, Tyler, Balmain, Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196775/
https://ncbi.nlm.nih.gov/pubmed/21807965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0219
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