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Genetic architecture of murine skin inflammation and tumor susceptibility

Germline polymorphisms in both model organisms and humans influence susceptibility to complex trait diseases such as inflammation and cancer(1,2,3,4). Mice of the Mus spretus species are resistant to tumor development, and crosses between Mus spretus and susceptible Mus musculus strains have been us...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Quigley, David A., To, Minh D., Pérez-Losada, Jesús, Pelorosso, Facundo G., Mao, Jian-Hua, Nagase, Hiroki, Ginzinger, David G., Balmain, Allan
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460995/
https://ncbi.nlm.nih.gov/pubmed/19136944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07683
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