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Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility

BACKGROUND: Germline polymorphisms can influence gene expression networks in normal mammalian tissues and can affect disease susceptibility. We and others have shown that analysis of this genetic architecture can identify single genes and whole pathways that influence complex traits, including infla...

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Hlavní autoři: Quigley, David A, To, Minh D, Kim, Il Jin, Lin, Kevin K, Albertson, Donna G, Sjolund, Jonas, Pérez-Losada, Jesús, Balmain, Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091303/
https://ncbi.nlm.nih.gov/pubmed/21244661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-1-r5
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