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Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis
Th17 cells reactive to the enteric microbiota are central to the pathogenesis of certain types of inflammatory bowel disease. However, Th17 cells display substantial developmental plasticity, such that some progeny of Th17 cell precursors retain a predominantly IL-17A(+) phenotype, whereas others ex...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460486/ https://ncbi.nlm.nih.gov/pubmed/26038559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415675112 |
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